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Temporal Cardiovascular Dynamics for Improved PPG-Based Heart Rate Estimation

Demirel, Berken Utku, Holz, Christian

arXiv.org Artificial Intelligence

Abstract-- The oscillations of the human heart rate are inherently complex and non-linear--they are best described by mathematical chaos, and they present a challenge when applied to the practical domain of cardiovascular health monitoring in everyday life. In this work, we study the non-linear chaotic behavior of heart rate through mutual information and introduce a novel approach for enhancing heart rate estimation in real-life conditions. Our proposed approach not only explains and handles the non-linear temporal complexity from a mathematical perspective but also improves the deep learning solutions when combined with them. We validate our proposed method on four established datasets from real-life scenarios and compare its performance with existing algorithms thoroughly with extensive ablation experiments. Our results demonstrate a substantial improvement, up to 40%, of the proposed approach in estimating heart rate compared to traditional methods and existing machine-learning techniques while reducing the reliance on multiple sensing modalities and eliminating the need for post-processing steps. Healthy biological systems exhibit complex patterns of variability that can be described by mathematical chaos [1], [2]. A healthy heart is not a metronome; instead, its complex and constantly changing oscillations enable the cardiovascular system to rapidly adjust to sudden physical and psychological challenges to homeostasis [2]. Therefore, measuring heart rate (HR) during daily life has significant importance in monitoring individuals' health.


Robust Photoplethysmography Signal Denoising via Mamba Networks

Chiu, I, Liu, Yu-Tung, Wang, Kuan-Chen, Wei, Hung-Yu, Tsao, Yu

arXiv.org Artificial Intelligence

Photoplethysmography (PPG) is widely used in wearable health monitoring, but its reliability is often degraded by noise and motion artifacts, limiting downstream applications such as heart rate (HR) estimation. This paper presents a deep learning framework for PPG denoising with an emphasis on preserving physiological information. In this framework, we propose DPNet, a Mamba-based denoising backbone designed for effective temporal modeling. To further enhance denoising performance, the framework also incorporates a scale-invariant signal-to-distortion ratio (SI-SDR) loss to promote waveform fidelity and an auxiliary HR predictor (HRP) that provides physiological consistency through HR-based supervision. Experiments on the BIDMC dataset show that our method achieves strong robustness against both synthetic noise and real-world motion artifacts, outperforming conventional filtering and existing neural models. Our method can effectively restore PPG signals while maintaining HR accuracy, highlighting the complementary roles of SI-SDR loss and HR-guided supervision. These results demonstrate the potential of our approach for practical deployment in wearable healthcare systems.




Foundation Model Hidden Representations for Heart Rate Estimation from Auscultation

Nie, Jingping, Tran, Dung T., Thakkar, Karan, Kowtha, Vasudha, Huang, Jon, Avendano, Carlos, Azemi, Erdrin, Mitra, Vikramjit

arXiv.org Artificial Intelligence

Auscultation, particularly heart sound, is a non-invasive technique that provides essential vital sign information. Recently, self-supervised acoustic representation foundation models (FMs) have been proposed to offer insights into acoustics-based vital signs. However, there has been little exploration of the extent to which auscultation is encoded in these pre-trained FM representations. In this work, using a publicly available phonocardiogram (PCG) dataset and a heart rate (HR) estimation model, we conduct a layer-wise investigation of six acoustic representation FMs: HuBERT, wav2vec2, wavLM, Whisper, Contrastive Language-Audio Pretraining (CLAP), and an in-house CLAP model. Additionally, we implement the baseline method from Nie et al., 2024 (which relies on acoustic features) and show that overall, representation vectors from pre-trained foundation models (FMs) offer comparable performance to the baseline. Notably, HR estimation using the representations from the audio encoder of the in-house CLAP model outperforms the results obtained from the baseline, achieving a lower mean absolute error (MAE) across various train/validation/test splits despite the domain mismatch.


An LLM-Powered Agent for Physiological Data Analysis: A Case Study on PPG-based Heart Rate Estimation

Feli, Mohammad, Azimi, Iman, Liljeberg, Pasi, Rahmani, Amir M.

arXiv.org Artificial Intelligence

Large language models (LLMs) are revolutionizing healthcare by improving diagnosis, patient care, and decision support through interactive communication. More recently, they have been applied to analyzing physiological time-series like wearable data for health insight extraction. Existing methods embed raw numerical sequences directly into prompts, which exceeds token limits and increases computational costs. Additionally, some studies integrated features extracted from time-series in textual prompts or applied multimodal approaches. However, these methods often produce generic and unreliable outputs due to LLMs' limited analytical rigor and inefficiency in interpreting continuous waveforms. In this paper, we develop an LLM-powered agent for physiological time-series analysis aimed to bridge the gap in integrating LLMs with well-established analytical tools. Built on the OpenCHA, an open-source LLM-powered framework, our agent features an orchestrator that integrates user interaction, data sources, and analytical tools to generate accurate health insights. To evaluate its effectiveness, we implement a case study on heart rate (HR) estimation from Photoplethysmogram (PPG) signals using a dataset of PPG and Electrocardiogram (ECG) recordings in a remote health monitoring study. The agent's performance is benchmarked against OpenAI GPT-4o-mini and GPT-4o, with ECG serving as the gold standard for HR estimation. Results demonstrate that our agent significantly outperforms benchmark models by achieving lower error rates and more reliable HR estimations. The agent implementation is publicly available on GitHub.


EnhancePPG: Improving PPG-based Heart Rate Estimation with Self-Supervision and Augmentation

Benfenati, Luca, Belloni, Sofia, Burrello, Alessio, Kasnesis, Panagiotis, Wang, Xiaying, Benini, Luca, Poncino, Massimo, Macii, Enrico, Pagliari, Daniele Jahier

arXiv.org Artificial Intelligence

Heart rate (HR) estimation from photoplethysmography (PPG) signals is a key feature of modern wearable devices for health and wellness monitoring. While deep learning models show promise, their performance relies on the availability of large datasets. We present EnhancePPG, a method that enhances state-of-the-art models by integrating self-supervised learning with data augmentation (DA). Our approach combines self-supervised pre-training with DA, allowing the model to learn more generalizable features, without needing more labelled data. Inspired by a U-Net-like autoencoder architecture, we utilize unsupervised PPG signal reconstruction, taking advantage of large amounts of unlabeled data during the pre-training phase combined with data augmentation, to improve state-of-the-art models' performance. Thanks to our approach and minimal modification to the state-of-the-art model, we improve the best HR estimation by 12.2%, lowering from 4.03 Beats-Per-Minute (BPM) to 3.54 BPM the error on PPG-DaLiA. Importantly, our EnhancePPG approach focuses exclusively on the training of the selected deep learning model, without significantly increasing its inference latency


Model-driven Heart Rate Estimation and Heart Murmur Detection based on Phonocardiogram

Nie, Jingping, Liu, Ran, Mahasseni, Behrooz, Azemi, Erdrin, Mitra, Vikramjit

arXiv.org Artificial Intelligence

Acoustic signals are crucial for health monitoring, particularly heart sounds which provide essential data like heart rate and detect cardiac anomalies such as murmurs. This study utilizes a publicly available phonocardiogram (PCG) dataset to estimate heart rate using model-driven methods and extends the best-performing model to a multi-task learning (MTL) framework for simultaneous heart rate estimation and murmur detection. Heart rate estimates are derived using a sliding window technique on heart sound snippets, analyzed with a combination of acoustic features (Mel spectrogram, cepstral coefficients, power spectral density, root mean square energy). Our findings indicate that a 2D convolutional neural network (\textbf{\texttt{2dCNN}}) is most effective for heart rate estimation, achieving a mean absolute error (MAE) of 1.312 bpm. We systematically investigate the impact of different feature combinations and find that utilizing all four features yields the best results. The MTL model (\textbf{\texttt{2dCNN-MTL}}) achieves accuracy over 95% in murmur detection, surpassing existing models, while maintaining an MAE of 1.636 bpm in heart rate estimation, satisfying the requirements stated by Association for the Advancement of Medical Instrumentation (AAMI).